DNA Alteration Details

System ID: 182

Gene: RAF1

Chromosome: 12

Variant Type: nonsense (stop-gain)

Deleterious: yes

Year Discovered: 2019

Is Defect?: Yes

Mode of Inheitance: Autosomal Recessive Lethal

Reference Sequence: GRCg6a

Variant Source: Naturally occurring variant

Genomic or Mitochondrial: g.5374854G>A

Coding DNA Sequence or Genomic DNA Sequence: c.175C>T

Protein Sequence: p.(R59*)

Reference Website: Visit website

Verbal Description: a single nucleotide change has ocurred in the genomic sequence at position 5,374,854 on chromosome 1. The original nucleotide G (guanine) at this position is replaced by A (adenine).

Trait: Disease -> Disease: Wingless-2

Breeds: NA