Gene: SOX5

Chromosome: 1

Year Discovered: 2009

Is Defect?: No

Variant Source: Naturally occurring variant

Genomic or Mitochondrial:

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Verbal Description: Pea-comb is caused by a massive amplification of a duplicated sequence located near evolutionary conserved non-coding sequences in intron 1 of the gene encoding the SOX5 transcription factor." The pea-comb mutant phenotype results from large-scale amplification of this duplication: pea comb alleles typically have 20-40 copies of the duplicated sequence which must be sufficient to interfere with transcription."

Breeds: Japanese game fowl